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Zepbound (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is FDA-approved along with increased physical activity and a reduced-calorie diet for chronic weight management in adults with a starting body mass index (BMI) of: 30 kg/m^2 or higher (obesity) 27 kg/m^2 or higher (overweight) with at least one weight-related condition such as high cholesterol, high blood pressure (hypertension), type 2 diabetes, heart disease, or obstructive sleep apnea

PMID: 28512250

J., Ow-Yang, C

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Established examples include exenatide, liraglutide, dulaglutide, semaglutide, and lixisenatide

The impact of structured exercise programs on metabolic syndrome and its components: a systematic review