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In contrast, M-CuP showed negligible binding to either target, with maximal responses below 5 response units (RU) across all tested concentrations, confirming the essential role of multivalent architecture in cooperative target engagement

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The 7-nAChR-selective antagonist methyllycaconitine (1 g/kg) delivered intraperitoneally nullified the neuroprotective effects of curcumin on animal behaviour and TH immunoreactivity

10.1177/1352458517711568 21 CobleyJ

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