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Patients should always verify that their compounding pharmacy holds a valid state license, employs a licensed pharmacist, and maintains proper sterilization protocols

Suspected adverse reactions to medicines including those encountered in clinical trials can be reported in the UK via the MHRA Yellow Card Scheme at yellowcard.mhra.gov.uk

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Start new supplements at the lowest recommended dose and increase gradually over 24 weeks

ICANS, closely associated with CRS, results from the rupture of the BBB caused by cytokine-mediated endothelial activation, which leads to immune cell infiltration, stress in astrocytes and pericytes, excitotoxicity, and neuroinflammation