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As an alternative methyl donor, betaine plays a central role in maintaining methylation capacity, and its depletion may contribute to elevations in S-adenosylhomocysteine and impaired methyltransferase activity

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Neuroendocrinol Lett 29(1):117124 Delgado-Ocaa S, Cuesta S (2024) From microbes to mind: germ-free models in neuropsychiatric research