Public reimbursement, HTA-style conservatism, and price revisions dominate adoption not self-pay hype
Additionally, epigenetic differences, such as increased methylation of protective genes, such as DUSP9, in females, may influence insulin sensitivity and drug response [49, 51]
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At the same time, some evidence suggests that certain GLP-1 drugsespecially semaglutidemay be associated with temporary worsening of diabetic retinopathy in patients who already have retinal disease, particularly when glucose improves quickly
Today, there are GLP-1 drugs made for diabetic patients (e.g., Ozempic and Mounjaro) and GLP-1s intended for weight loss patients (e.g., Wegovy and Zepbound)
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