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However, increases in circulating NAD precursors do not necessarily translate into proportional expansion of tissue-specific redox capacity, as precursor metabolism and systemic NAD pools are strongly influenced by microbial conversion and circulatory metabolism [109]

Funding This work was financially supported by the National Institutes of Health (NIH) grants [R00CA215301 and R01EB034360], the National Science Foundation (NSF) grant [2326628], and the Cancer Prevention and Research Institute of Texas (CPRIT) grant [RP240498] to G.O

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