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Dexmedetomidine, an 2-adrenergic receptor (2-AR) agonist, has been shown to have renal protective effects against ferroptosis-mediated renal IRI and the inflammatory response through the suppression of ACSL4 [70]

141B:947956 James SJ, Melnyk S, Jernigan S, Hubanks A, Rose S, Gaylor DW (2008) Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism

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Expanded Indications : Clinical trials currently underway are exploring applications for conditions ranging from fatty liver disease to kidney protection, potentially expanding the patient population significantly

(2012) 161:927932.e2