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The GPX4 gene is located on chromosome 19p13.3 and is composed of 8 exons that generate three alternatively spliced mRNAs that encode several distinct protein isoforms that exhibit distinct subcellular sites of localization including the nucleus, the mitochondria, and the cytosol

(2021, March 17)

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Unlike some signaling molecules that act through a single receptor target, amylin biology involves a more complex receptor network

Intriguingly, LL-37 also has anti-inflammatory properties in certain contexts, making it a dual-natured molecule