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A pharmacogenetics review notes that for amphetamine like agents, CYP2D6 accounts for a smaller fraction of overall clearance than expected, so genetic variability has less impact on acute toxicity than with classic CYP2D6 substrates like atomoxetine

Yes, side effects are possible

And like the first one's almost a false success point, and then you could revert easily until you get past the second point

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the distance from the proximal fold allows estimation of the time elapsed since the insult