Deep brain stimulation of the subthalamic nucleus does not increase the striatal dopamine concentration in parkinsonian humans
Semaglutide is metabolized through fatty acid beta-oxidation and peptide backbone cleavage
Because none of these peptides are FDA-approved for the uses we describe, the supervision around them is a real part of the treatment: baseline labs, a written protocol, follow-up testing, and an honest conversation about where the evidence sits for each molecule
They are often used alongside other tools like appetite suppressants, nutritional counseling, or meal replacements
BPC-157 does not require post-cycle therapy since it does not affect hormonal systems and produces no rebound effects
Recognizing SAGE-DM emphasizes the need for personalized diagnosis and treatment strategies tailored to the unique biology of aging