While immune signatures had resolved in the kidney, they remained modestly elevated in the heart
For primary weight loss in patients with BMI above 30, standard titration to 2.4 mg remains the evidence-based choice per the STEP trial program (Wilding et al., N Engl J Med, 2021)
Thyroid function and the risk of fibrosis of the liver, heart, and lung in humans: a systematic review and meta-analysis
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Seek emergency services if you experience: Persistent vomiting Severe abdominal pain Inability to keep food or fluids down Symptoms that worsen instead of improve Signs of dehydration Concerns about rapid or excessive weight loss Changes in mood, depression or suicidal thoughts GLP-1 medications can be helpful for managing blood sugar and supporting weight-related goals, but its normal to have questions as your body adjusts
The landmark STEP trials that demonstrated Wegovy's efficacy (13.6% average body weight reduction over 68 weeks) are based on semaglutide itself, not Wegovy's specific formulation