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742 In ischemic stroke, sudden hypoxia of neurons triggers a large release of glutamate, which induces hypoxia depolarization and leads to rapid cell death

Less common but more serious side effects can include pancreatitis, gallbladder problems, or kidney issues

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It may also be beneficial to consider individuals at high risk for prodromal PD

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[12] [13] The Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMA) continue to monitor the safety profile of GLP-1 agonists through routine pharmacovigilance