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PLoS ONE 6 , e24957 (2011)

A., Camargo Jr, C

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To account for the variation in urinary concentrations between subjects, the creatinine-normalized excretion of the urine metabolites was determined

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In plasma, only 13% of sex hormones are biologically active in their free form, while approximately 38% of estrogens and 44% of androgens are bound to SHBG [182]