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Instead, existing cartilage cells (#chondrocytes) were reprogrammed toward a more youthful gene-expression profile, decreasing #inflammatory and cartilage-degrading cell subtypes and increasing cells that support healthy articular cartilage and its extracellular matrix

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van der Valk ME, Mangen M-JJ, Severs M, van der Have M, Dijkstra G, van Bodegraven AA, Fidder HH, de Jong DJ, van der Woude CJ, Romberg-Camps MJL, Clemens CHM, Jansen JM, van de Meeberg PC, Mahmmod N, van der Meulen-de Jong AE, Ponsioen CY, Bolwerk C, Vermeijden JR, Siersema PD, Leenders M, Oldenburg B, COIN study group and the Dutch Initiative on Crohn and Colitis (2016) Evolution of costs of inflammatory bowel disease over two years of follow-up