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An analysis using five years of medical records from tens of thousands of adults diagnosed with obesity and Type 2 diabetes showed "statistically significant increases" of the conditions, the American Academy of Orthopedic Surgeons said in a statement

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Efficacy and safety of Tirzepatide monotherapy compared with dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono): a double-blind, multicentre, randomised, phase 3 trial