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The trials did not specify: The type of hair loss Whether shedding was clinically diagnosed or self-reported Whether hair loss correlated with the speed of weight loss or diet Because hair loss occurs naturally in the population, it is difficult to determine whether the medication itself played a role

Because glutamine is the source of -KG, glutaminase inhibitors such as BPTES interfere with -KG homeostasis and lead to inhibited proliferation in cancer cells carrying this mutant IDH1 (Seltzer et al., 2010)

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While these approaches can sometimes help manage pain or relieve acute discomfort, they often fall short of providing lasting relief for many patients

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However, for others, it can be distressing and lead to a decreased enjoyment of food altogether