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Similarly, triptolide was implicated in the treatment of the breast cancer cell line MCF-7 through the induction of autophagy-mediated cell death by increasing ERK1/2 phosphorylation 43

The program of qPCR reaction included 95 C for 10 min, 40 cycles of 95 C for 5 s and 60 C for 15 s

However, the response to ICIs is heterogeneous, and biomarkers like PD-L1 expression levels have been correlated with treatment outcomes

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References Shiue SJ, Cheng CL, Shiue HS, Chen CN, Cheng SW, Wu LW, Jargalsaikhan G, Chan TS, Lin HY, Wu MS