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Biochemistry 64 , 26992711 (2025)

Therapeutic interventions targeting this axis, such as resveratrol, and quercetin, show promise by simultaneously modulating gut-joint signaling and suppressing ferroptosis, potentially achieving intestinal barrier recovery and chondrocyte rescue

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M., DeSilva, D., Pickart, L., & Aust, S

NAD + metabolic disturbance NAD + has neuroprotective effects in acute axonal injury, chronic nerve stress, and different neurodegenerative diseases associated with excitotoxicity [116]