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Side Effects Compared The side effect profiles are quite different because the drugs work through different systems

[9] For weight management, semaglutide (Wegovy) may be prescribed through specialist weight management services for eligible patients with a BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) and is typically prescribed for up to 2 years (NICE TA875)

Like other GLP-1R agonists, when used alone or treated with non-insulin secretagogues, DUL treatment is associated with weight loss or decreased weight gain (107)

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Notably, these medications are not recommended for patients with severe gastroparesis or other significant gastrointestinal disorders, as stated in their FDA labeling

Micro-dosing allows the body to adapt gradually, fostering long-term metabolic improvements without drastic interventions