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Symptoms associated with B12 deficiency may include: Persistent fatigue or weakness Memory impairment or confusion Nerve-related issues such as numbness or tingling Mood fluctuations or depression Pale or yellowish skin A B12 deficiency can affect anyone, but older adults are particularly vulnerable

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The remission rate was unchanged by beta-carotene treatment.49 In vitro evidence suggests synthetic beta-carotene does not have the radioprotective effect noted with the natural form