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Notably, we produced acetylated SnCE1 protein on the background of the catalytically inactive mutant SnCE1 C256A in order to be able to assess a possible impact of acetylation on the SnCE1 oligomeric state and to obtain SnCE1 protein acetylated specifically on these individual lysine side-chains as wild type SnCE1 is acetylated at multiple sites and forming a monomer in solution (Supplementary Figs
This does not mean higher doses are dangerous
TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
2018 Oct 18;6(4)
These results contribute to the expanding body of evidence supporting the neuroprotective role of Ang-II stimulating drugs
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