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Adult use today rests on practitioner experience, published reviews, and pharmacokinetic (PK) studies, not large modern randomized controlled trials

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- Follow Up Appointments: Schedule regular follow-ups to ensure you maintain optimal levels of B12

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( We list all final C-APC exclusion categories for CY 2026 in Addendum J to this final rule with comment period (which is available via the internet on the CMS website at )