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Notably, the acetylation of histones plays a role in the regulation of gene expression by facilitating transcription (i.e., mRNA synthesis), while deacetylated histones are usually associated with chromatin compaction and gene silencing

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Increased intestinal cholesterol absorption in the sluggish intestine is another lithogenic predisposing factor, as shown in the murine cholelithogenic model [73, 74]

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10.2174/1381612826666200523180301 53 PerovicD.KolencD.BilicV.SomunN.DrmicD.ElabjerE.et al (2019)