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Uptake of uric acid by pancreatic -cells Urate transporters include, (i) urate transporter 1/solute carrier family 22, member 12 (URAT1/SLC22A12), (ii) ATP-binding cassette subfamily G, member 2/breast cancer resistance protein (ABCG2/BCRP), and (iii) glucose transporter 9 (GLUT9/SLC2A9) [8]

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Cerebrospinal fluid (20 ml) was drawn from the L1-L2 interspace using Gertie-Marx needles 107,108 in the prone position under fluoroscopic guidance by interventional radiologists

Each route has different bioavailability, meaning the proportion of the administered dose that reaches systemic circulation

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