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4 Medication-based therapeutic approaches for DKD 4.1 Inhibitors of the reninangiotensinaldosterone system (RAASi) Blockade of the RAAS remains the foundational therapy for DKD, supported by robust evidence from landmark randomized controlled trials

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In terms of opioids, reportedly 22.3% of the 2.5 million Americans with OUD have received treatment with an OUD indicated medication in the past year (though some estimates put the number of Americans with OUD at ~7 million)

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