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A1C reduction of 1.7-2.0% across doses at 40 weeks

With files from CBC's Alison Northcott and Marcy Cuttler

Over months and years, this sustained assault gradually destroys the gland's ability to produce thyroid hormones T3 and T4

Some fatigue is expected

As a class effect shared with GLP-1 receptor agonists, there is a precautionary concern regarding thyroid C-cell tumours, based on animal studies

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