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In addition, a 48-week phase 2b randomized, placebo-controlled trial (involving 293 adults with obesity and biopsy-confirmed MASH and fibrosis stage F1-F3) reported that once-weekly subcutaneous survodutide at doses of 2.4 mg, 4.8 mg, or 6.0 mg was superior to placebo for histological improvement in MASH without worsening of liver fibrosis, warranting further investigation in phase 3 trials (Sanyal et al., 2024[67])

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For others, resurfacing the affected skin with a Fractional Resurfacing Laser have had some success in unplugging the follicles

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