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Vitamin C, found in citrus juices and vitamin supplements, can hinder the absorption of Adderall and make it less effective

Piperine co-administration inhibits phase II glucuronidation and sulphation via competitive enzyme inhibition, thereby augmenting systemic curcumin exposure by an estimated 2- to 20-fold in human pharmacokinetic studies, although the magnitude of enhancement varies with dose and timing (Figure 1)

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