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Lehmann R, Graziano J, Brockmann J et al (2015) Glycemic control in simultaneous islet-kidney versus pancreas-kidney transplantation in type 1 diabetes: a prospective 13-year follow-up

As far as peptide 20 is concerned, the peptide binding pocket of both GLP-1R and GCGR closely resembled that of GLP-1 and GCG bound structures, where notable conformational change was only observed in the ECL1 of GIPR

However, these observations need to be confirmed by future trials [138]

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The rate of GLP-1 receptor agonist use rose more than threefold during the study period, from 8.6% in 2018 to 26.8% in 2023, the researchers found

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