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Statements Author contributions JM wrote the paper with input from AV regarding content and layout

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European neurology , 23 5, 372-85

Non-reversible side effects to the heart, joints, and liver may occur due to abnormal growth

Symptoms may include: Numbness, tingling, burning, or "wrong" sensations (parasthesias) anywhere in the body Gut motility disruption or enzyme secretion issues related to nervous system involvement Autonomic symptoms alongside peripheral pain or sensory changes Pain and fatigue patterns consistent with fibromyalgia, POTS, or connective tissue disorders The biopsy also tests for deposition of alpha-synuclein and amyloid - misfolded proteins that can reflect elevated total stress burden and are associated with Parkinson's and Alzheimer's disease respectively