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They can increase oxidative stress and inflammation, disrupt the gut microbiome, and impact the methylation pathway

The ability to apply it directly to the affected area is what brought it to the attention of those treating hair loss

PMID 18065594

When a mechanism repeatedly looks good in small or preliminary studies and then fails in large ones, the problem is usually not the individual trial but the strength of the original inference

They cannot offer the physician who has known a patient for years, who understands their history, their hesitations, and what has not worked before

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