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Providing support for a causal link between a negative energy state and increased Parasutterella abundance, a rat model of obesity, which showed similar Parasutterella relative abundances in animals maintained on HFD and those maintained on normal chow but exhibited a treatment-induced increase in Parasutterella relative abundance, displayed a negative correlation between Parasutterella and body weight 82

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He encourages people to take it easy and give themselves time to adjust, whether that involves pulling back temporarily or redefining what a good workout looks like right now

The peptide-hormone literature runs from decades-old approved drugs to compounds never tested in a human

However, it is imperative to note that findings from animal models cannot be directly extrapolated to clinical trials in humans