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DON was found to be the top predictor that impacted polar metabolite clusters PC2, PC4, PC10, and PC11, as shown in Fig

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Gut-restricted peptide pharmacology Examined as a model of a locally-acting, minimally-absorbed oral peptide

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3.2 Therapeutic potential via paracrine mechanisms The therapeutic effects of MSCs are primarily mediated through their paracrine activity, which involves the secretion of bioactive factorssuch as growth factors, chemokines, cytokines, and EVsto modulate the local microenvironment (Pittenger et al., 2019