Luminescence signal was assessed over time (020 min) in the presence of increasing concentrations of GLP-1 and TT-OAD2
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GSH depletion, reduced GPX4 activity, and decreased cellular antioxidant capacity collectively lead to lipid peroxidation and ROS accumulation, ultimately resulting in ferroptosis
BPC-157 has a well-characterised neuroprotective profile across ischaemia (MCAO infarct reduction), TBI (CCI contusion volume reduction), SCI (BBB locomotor score improvement), Parkinsons (MPTP/6-OHDA dopaminergic protection), and excitotoxicity models
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