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Abbreviations CVD: Cardiovascular disease ROS: Reactive oxygen species PUFAs: Polyunsaturated fatty acids GPX4: Glutathione peroxidase 4 AS: Atherosclerosis ACSL4: Long-chain-fatty-acid-CoA ligase 4 LPCAT3: Lysophosphatidylcholine acyltransferase 3 AdA: Adrenic acid MUFAs: Monounsaturated fatty acyl tails NCOA4: Nuclear Receptor Coactivator 4 SLC7A11: Solute carrier family 7 member 11 GSH: Glutathione FSP1: Ferroptosis suppressor 1 NOS2: Nitric oxide synthase 2 HSCs: Hematopoietic stem cells MI: Myocardial infarction HIF-1: Hypoxia-inducible factor-1 NRF2: Nuclear factor erythroid 2-related factor 2 AF: Atrial fibrillation HF: Heart failure VTE: Venous thromboembolism COVID-19: Coronavirus disease 2019 SARS-CoV-2: Severe acute respiratory syndrome coronavirus type 2 HO-1: Haem oxygenase-1 YAP1: Yes-associated protein 1 STAT3: Signal transducer and activator of transcription 3 IRF3: Interferon regulatory factor 3 SFXN1: Sideroflexin 1 References Yarovinsky TO, Su M, Chen C, Xiang Y, Tang WH, Hwa J

The mixed bed system must be paired with upstream pretreatment equipmentsuch as reverse osmosis, water softening, or activated carbon filtrationto minimize suspended solids, organic matter, residual chlorine, and water hardness in the influent, thereby preventing contaminants from entering the mixed bed directly

Titov, A

Phase 1 reaction involves oxidation, reduction, hydrolysis, hydration and many other rare chemical reactions

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demonstrated that the luminal androgen receptor (LAR) subtype of TNBC is characterized by the upregulation of glutathione metabolism, which allowed the utilization of Glutathione peroxidase 4 (GPX4) inhibitors to induce ferroptosis of TNBC [15]