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Psychiatry 20 , 4151 (2016)

Estudos em modelos animais sugerem efeitos ansiolticos e antidepressivos, possivelmente mediados pela interao com os sistemas dopaminrgico e serotoninrgico

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The gene deleted in a mutant was marked with a number in the name of the constructed strain (Table 1)

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In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]