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Phase 2 data published in the New England Journal of Medicine (2023) reported mean body weight reductions of up to 24.2% at the highest dose cohort over 48 weeks, surpassing outcomes seen with dual or single-receptor agents in equivalent trials

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doi.org/10.1056/NEJMoa2032183 2 Look M, et al

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Gastrointestinal symptoms and occasional psychiatric concerns require monitoring

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