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Comstock SS, et al

Wortha, Katharina A

The Phase-3 Pipeline: Beyond Simple GLP-1 Agonism Current Phase-3 candidates are moving toward poly-agonismtargeting multiple receptors simultaneously to maximize weight loss and glycemic control

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BPC 157, a stable pentadecapeptide derived from a gastric cytoprotective protein, is notable for its resistance to proteolytic degradation and acidic conditions, making it particularly advantageous for preclinical modeling (Jzwiak et al

Alteration of KEAP1-NRF2 activity in ALS The human brain is an organ with elevated demand of energy, relying on oxidative metabolism and high consumption of O 2 to perform its functions [68]