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Nguyen HL, Linh HQ, Krupa P et al (2022) Amyloid dodecamer disrupts the neuronal membrane more strongly than the mature fibril: understanding the role of oligomers in neurotoxicity

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It binds directly to v5 integrin, which is abundant in astrocytes, and the inhibition of v5 integrin in vitro effectively attenuates angiopoietin 2-induced astrocyte apoptosis