doi: 10.1089/ars.2020.8257 51 HuangZZhuangXXieCHuXDongXGuoYet al
Gallbladder disease: GLP-1 receptor agonists as a class have been associated with an increased risk of cholelithiasis (gallstones) and cholecystitis
In that population, it was not uncommon for people to inadvertently get pregnant because they had lost such a significant amount of weight that their ovulation kind of recalibrated. If people experienced similar rapid weight loss due to GLP-1s, she says, There is potential for them to start to re-ovulate. Yet results across weight-loss studies are inconsistent
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However, sensitivity analyses excluding this higher-risk study yielded comparable pooled estimates, and leave-one-out analyses showed consistent direction of effect across all exclusions