The brain thinks the body is overheating, so it launches a cooling response: blood vessels dilate, heart rate increases, and sweat glands activate
Body Composition Findings Data suggests weight reduction is largely derived from fat mass, with comparatively limited lean muscle loss
For many patients, killing back a disruptive overgrowth and then restoring diversity through diet and targeted pre- and post-biotic strategies is the fastest path to consistent stool habits and symptom relief
Albiglutide: first global approval
On the other hand, some data on chronic administration of long acting GLP1RAs have established that deceleration of gastric emptying does continue albeit less compared to short-acting GLP1RAs
The larger and longer-lasting (5 years) SOUL trial is ongoing and will determine if oral semaglutide has CV benefits in patients with T2D and CVD or chronic kidney disease (22)