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Lee et al., 2012)

However, amid cheering for our favorite teams, its easy to lose focus on the health and weight loss [...] March Madness for Your Metabolism: Stay on Track with Your Weight Loss Goals at Park CityStefani Hillin2025-05-30T16:07:39-06:00 Heart-Healthy Weight Loss: How GLP-1 Medications Can Help Reduce Heart Disease Risk Stefani Hillin2025-06-20T17:30:47-06:00 Weight significantly impacts cardiovascular risk, especially excess abdominal fat, which raises the chances of high blood pressure, high cholesterol, and insulin resistancemajor contributors to heart disease

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The dual agonism is why tirzepatide produces greater weight loss than semaglutide, a selective GLP-1 agonist, as seen in trials comparing the two agents

Both medications have similar side effects, mainly gastrointestinal, with a rare risk of severe issues like thyroid tumors