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The receptor, coupled to a G protein, stimulates adenylate cyclase, which converts ATP into cyclic AMP (cAMP)

Of the 110 schizophrenia patients, 26 (23.6%) had a family history of mental disorders

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Increased FAO may be an adaptive response in patients with NAFLD attempting to reduce the lipid overload and lipotoxicity, but also produces ROS and excessive FAO may overwhelm the capacity of the anti-oxidant defense system and induce oxidative stress

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