Regarding the efficacy of oral lipoic acid supplementation, an initial short-term study in 24 patients with type 2 diabetes mellitus found that the symptoms of peripheral neuropathy improved in those who took 600 mg of lipoic acid three times a day for three weeks compared to those who took a placebo (75)
They have no known negative interactions, operate on separate pathways, and are more effective as a combined protocol than either is alone
Joseph Brewer evaluated 112 patients with a prior diagnosis of ME/CFS
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