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In addition to activation of the KEAP1/Nrf2 system by oxidation of KEAP1 cysteine residues, some cysteine residues of KEAP1 can interact with certain electrophilic compounds

The following day the prepulse-inhibition of startle response was assessed by exposing rats to a startle stimulus (105 dB for 20 ms) preceded (100 ms) by a pre-pulse (77, 80 and 83 dB for 10 ms) repeated 10 times for each prepulse intensity at pseudo-random interval (1520 s, average of 17.5 s)

Patients who drink at this level on injection nights consistently report that their week-4 sleep and energy improvements either never arrive or vanish

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doi: 10.1152/ajplung.1998.275.5.L861