Animal protocols range from 10 g/kg to 1 mg/kg administered subcutaneously, intraperitoneally, or orally, typically daily for 7-30 days depending on injury model
Although these drugs can be used to combat obesity (at this stage we understand most obesity usage is off label[2]), over the last fifteen years they have been predominantly used to treat type 2 diabetes
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In summary, after BPC 157 therapy, rats with a ligated bile duct exhibited no portal and caval hypertension, ameliorated aortal hypotension, markedly attenuated superior sagittal sinus hypertension, and no prolonged QTc interval
Available online: [DOI] [PubMed] [Google Scholar] 77.Lisco G., De Tullio A., Disoteo O., Piazzolla G., Guastamacchia E., Sabb C., De Geronimo V., Papini E., Triggiani V
N Engl J Med 2023;389:10691084