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For most users these effects subside as the skin adapts, but a meaningful minority cannot tolerate tretinoin at full strength, and it is generally contraindicated in pregnancy and while breastfeeding
This demonstrates that the measure would provide useful data for the public and for hospital quality improvement
Used For: Skin brightening, reducing hyperpigmentation, fading dark spots, improving uneven skin tone, reducing dullness, supporting collagen production, antioxidant protection, and improving overall skin radiance
Additionally, skin irritation from polyphenols has been documented in some research, meaning that skincare products containing urolithin A may also have this risk.22 Finally, on the topic of pomegranate, since urolithin A is often derived from compounds of the fruit, it may interact with the same drugs (e.g., those metabolized by cytochrome P450, or CYP450, enzymes).23 24 These include but arent limited to:25 ACE inhibitors Blood pressure medications Statins (cholesterol-lowering medication) Warfarin (blood thinner) Sildenafil Anticonvulsants Sulfonylureas Buspirone (an anti-anxiety medication) Metformin Piracetam (a nootropic drug) Theophylline (used in asthma and COPD) However, Dr