These medications are large peptide molecules with molecular weights exceeding 4,000 daltons, a size that typically restricts transfer across the intestinal barrier
It is designed to deliver propionate, a short-chain fatty acid, to the large intestine, where it can stimulate the release of satiety hormones including GLP-1 and Peptide YY
Finally, equine hepcidin, an antimicrobial peptide also involved in iron homeostasis, was discovered and analyzed concerning its tissue distribution
10.3389/fphar.2022.750507 77 WuS.-I.ChenV
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