It is a GHRH analog, FDA-approved as Egrifta, and in its trials it reliably raised IGF-1 and dropped visceral fat in people (Falutz, NEJM 2007)
Tio D, van Montfrans C, Ruijter CGH, Hoekzema R, Bekkenk MW
Moving on to cardiometabolic markers we see large drops in fasting insulin, and small but modest changes in glucose, A1c, and lipid markers consistent with weight loss
That is especially true in aging cats, where oxidative stress tends to climb over time
The presence of high serum bicarbonate could indicate chronic respiratory acidosis [typical of chronic obstructive pulmonary disease (COPD)] or metabolic alkalosis (secondary to vomiting, use of thiazide diuretics, or excess mineralocorticoids) (336)
Journal of Clinical Medicine, 5 (4), 48