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By activating both incretin pathways, tirzepatide enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, delays gastric emptying, and reduces appetite through central nervous system effects

Adults, take 2 capsules daily

North Carolina made a similar switch in coverage policy last month, citing the high cost of covering the medications for obesity

Whats in development

Common Side Effects The most frequently reported side effects of GLP-1 agonists include: Gastrointestinal Symptoms: Nausea, vomiting, diarrhoea, and constipation are the most common adverse effects associated with GLP-1 receptor agonists

However, for some individuals it can be uncomfortable enough to affect daily life, eating habits, and motivation to continue treatment